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Title a Rapid and Analytically Sensitive LC-MS method for the simultaneous analysis of a panel of steroid hormones for Clinical research
Summary in this sudy, a rapid clinical research method for LC-MS/MS measurement of T, DHEAS, A4 and 17OHP has been developed. The method is suitable for research use and the small volume of serumused (50 µl) is desirable for clinical research laboratory=ies that are sample limited.
Category 2. Symbiosis Application Notes

These are application notes that have been made in our application lab. They were based on customer demo's and customer method development requests. They include sorbent screening, a calibration curve and are optimized for carry over. They are not always (completely) validated
Matrix Serum
Market OSM Clinical
Technique online SPE
Cartridge Waters MassTrak C8 Online SPE Cartridges
Detection Waters XEVO TQ-S
Compounds Androstenedione, Testosterone, Dyhydroepiandrosterone sulfate, DHEAS, DHEA and 17-Hydroxyprogesterone, 17 OHP
Compound Group Hormones, steroids, steroid hormones
Sample_volume 50µL
Contact Laura Owen and Brian Keevil
Account University Hospital South Manchester, UK
Published poster technical Brief
Date 04.08.2015
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Status published